Molecular analysis of the camp- response element [CRE] elements in the promoter region and exon 1 of the survival of motor neuron 2 [SMN2] gene in Malaysian spinal muscular atrophy patients; to elucidate their role in circumscribing the clinical severity of SMA
Objective: In the Spinal muscular atrophy [SMA] genes [SMN1 and SMN2 genes]; the CRE-II elements at -400 bp in the promoter region of the SMN genes and CRE-I element at +108 bp in the exon 1 of the SMN genes, are reported to have a role in c-AMP induce expression of the SMN genes through its binding...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/5586/1/FH02-FPSK-15-02353.jpg http://eprints.unisza.edu.my/5586/ |
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| Institution: | Universiti Sultan Zainal Abidin |
| Language: | English |
