Obesity Leads to Elevated Level of Circulating Cell-Free DNA

With the steadily growing number of studies in the issues related to obesity research, it is proven, that obesity might be related to wide number of body disorders, some of these disorders have been already studied and investigated, and some still needed more investigations, which has opened new hor...

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Main Authors: Atif Amin, Baig, Ahmad Zubaidi, A.latif, Nordin, Simbak, Tengku Muhammad Ariff, Raja Hussin
Format: Article
Language:English
Published: 2018
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Online Access:http://eprints.unisza.edu.my/5701/1/FH02-FP-19-24393.pdf
http://eprints.unisza.edu.my/5701/
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Institution: Universiti Sultan Zainal Abidin
Language: English
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spelling my-unisza-ir.57012022-02-23T03:31:36Z http://eprints.unisza.edu.my/5701/ Obesity Leads to Elevated Level of Circulating Cell-Free DNA Atif Amin, Baig Ahmad Zubaidi, A.latif Nordin, Simbak Tengku Muhammad Ariff, Raja Hussin R Medicine (General) With the steadily growing number of studies in the issues related to obesity research, it is proven, that obesity might be related to wide number of body disorders, some of these disorders have been already studied and investigated, and some still needed more investigations, which has opened new horizons to unlimite hypotheses about involvement of obesity in many physiological disorders. In the current opinion, we hypothesized to the conclusion that there is a correlation between obesity severity and elevated cfDNA levels in the circulation. This correlation is based on free radicals and oxidative stress hypothesis of cellular and molecular damage in cell injury, which in turn leads to a disorder in the whole body and enhances the inflammatory status. 2018-12 Article PeerReviewed text en http://eprints.unisza.edu.my/5701/1/FH02-FP-19-24393.pdf Atif Amin, Baig and Ahmad Zubaidi, A.latif and Nordin, Simbak and Tengku Muhammad Ariff, Raja Hussin (2018) Obesity Leads to Elevated Level of Circulating Cell-Free DNA. Current Trends in Biomedical Engineering & Biosciences How, 16 (4). pp. 1-4. ISSN 2572-1151
institution Universiti Sultan Zainal Abidin
building UNISZA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Sultan Zainal Abidin
content_source UNISZA Institutional Repository
url_provider https://eprints.unisza.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Atif Amin, Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
Tengku Muhammad Ariff, Raja Hussin
Obesity Leads to Elevated Level of Circulating Cell-Free DNA
description With the steadily growing number of studies in the issues related to obesity research, it is proven, that obesity might be related to wide number of body disorders, some of these disorders have been already studied and investigated, and some still needed more investigations, which has opened new horizons to unlimite hypotheses about involvement of obesity in many physiological disorders. In the current opinion, we hypothesized to the conclusion that there is a correlation between obesity severity and elevated cfDNA levels in the circulation. This correlation is based on free radicals and oxidative stress hypothesis of cellular and molecular damage in cell injury, which in turn leads to a disorder in the whole body and enhances the inflammatory status.
format Article
author Atif Amin, Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
Tengku Muhammad Ariff, Raja Hussin
author_facet Atif Amin, Baig
Ahmad Zubaidi, A.latif
Nordin, Simbak
Tengku Muhammad Ariff, Raja Hussin
author_sort Atif Amin, Baig
title Obesity Leads to Elevated Level of Circulating Cell-Free DNA
title_short Obesity Leads to Elevated Level of Circulating Cell-Free DNA
title_full Obesity Leads to Elevated Level of Circulating Cell-Free DNA
title_fullStr Obesity Leads to Elevated Level of Circulating Cell-Free DNA
title_full_unstemmed Obesity Leads to Elevated Level of Circulating Cell-Free DNA
title_sort obesity leads to elevated level of circulating cell-free dna
publishDate 2018
url http://eprints.unisza.edu.my/5701/1/FH02-FP-19-24393.pdf
http://eprints.unisza.edu.my/5701/
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