Registration of Positron Emission Tomography (PET) Image and Functional Near Infrared Spectroscopy (NIRS) Data
Functional near infrared spectroscopy (NIRS) is the optical imaging that measures changes of blood hemodynamic while positron emission tomography (PET) measure physiological condition of the interest area. NIRS has high temporal resolution while PET image has better spatial resolution compared, h...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/6372/1/FH02-FSK-19-28829.pdf http://eprints.unisza.edu.my/6372/ |
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| Institution: | Universiti Sultan Zainal Abidin |
| Language: | English |
| Summary: | Functional near infrared spectroscopy (NIRS) is the optical imaging that measures changes of
blood hemodynamic while positron emission tomography (PET) measure physiological condition of the
interest area. NIRS has high temporal resolution while PET image has better spatial resolution compared,
however, NIRS measures hemodynamic changes in the cortex region but not in deeper brain structures.
Therefore, this study is aimed to register the both image; the NIRS data on the PET image. The registration
of NIRS on PET image was done on eleven subjects which undergoes NIRS and PET scan separately. To
register the NIRS probe on the PET image, we did a transformation of NIRS probe coordinate to the PET
coordinate based on Polaris marker position attached to the NIRS cap. The coordinate of these markers is
obtained using the optical tracking system, Polaris. The resulting image forms PET and NIRS were visually
aligned as well as the coordinate of the marker obtained during the PET acquisition. The probe was
registered on the PET image using the in-house software. The registration done in this study is considered
successful as we can view the NIRS activation area on PET image. |
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