Isolation and antibiogram of Acinetobacter bauminnii recovered from human clinical specimen in a tertiary care setting from Lahore, Pakistan
Acinetobacter baumannii is non-fermentive oxygen-consuming Gram-negative coccobacilli pathogen that has appeared as an essential bacteria responsible for hospital-acquired infections. It also has proved itself as an opportunistic pathogen and colonises, especially in those patients which were immu...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | http://eprints.unisza.edu.my/6635/1/FH02-FP-19-35978.pdf http://eprints.unisza.edu.my/6635/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Universiti Sultan Zainal Abidin |
| Language: | English |
| Summary: | Acinetobacter baumannii is non-fermentive oxygen-consuming Gram-negative coccobacilli pathogen that has appeared as an
essential bacteria responsible for hospital-acquired infections. It also has proved itself as an opportunistic pathogen and
colonises, especially in those patients which were immunocompromised and were admitted in intensive care units (ICUs),
orthopaedic wards, gynae wards and medical wards. The present study was designed to isolate the A.baumannii recovered
from different wards of the hospital from various samples. The biochemical characterisation was done by analytical profile
index for non-Enterobacteriaceae (API 20NE) system and was subjected for antimicrobial susceptibility pattern. Human
clinical specimens like urine, blood, CSF, pus, sputum, HVS and other fluids were examined by the specific methods, and
Kirby-Bauer disk diffusion method was adopted according to the Clinical and Laboratory Standards Institute guidelines (CLSI)
for the examination of resistivity and susceptibility pattern of pathogens. A total of 150 isolates were recovered out of 912
specimens over the six months (July 2018 to December 2018) in a tertiary care hospital. A high proportion of isolates were
resistant against the Ampicillin-Salbactum (69.33%), Cefepime (64.67%), Ceftriaxone (61.33%) and Ceftazidime (60%)
whereas Papracillin-Tazobactam (66.67%), Tigecyclin (59.33%), Doxycyclin (56.67%) and Imipenem (55.33%) show maximum
efficacy against the isolated pathogens. By adopting the standard policies for the use of antibiotics, increasing resistance of A.
baumannii against different classes of drugs could be minimised. |
|---|