Population Differences in the Genetic Polymorphism of CYP2B6 May Impact on the Pharmacology of MMT

Objective: Introduced by the German as a synthetic opioid analgesic, methadone is used world-wide as a substitution treatment for opioid dependence. It is a chiral compound and its pharmacology is complex. This can further be complicated by population differences in the genetic polymorphisms of enzy...

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Bibliographic Details
Main Authors: Nasir, Mohamad, Nurfadhlina, Musa, Sean, Tan
Format: Article
Language:English
Published: KARGER 2015
Subjects:
Online Access:http://eprints.unisza.edu.my/7077/1/FH02-FP-16-05526.jpg
http://eprints.unisza.edu.my/7077/
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Institution: Universiti Sultan Zainal Abidin
Language: English