Small-scale Optimization of Recombinant Plasmodium knowlesi Apical Membrane Antigen 1 (rPkAMA1) Expression in Pichia pastoris

• Main Authors: Hoong, Chew Ching, Fatimah Nadiah, Haron, Aina, Azazi, Chua, Kek Heng, Lim, Yvonne Ai Lian, Lee, Ping Chin
• Format: Article
• Language: English
• Published: Penerbit Universiti Sultan Zainal Abidin 2020
• Subjects: QH301 Biology
• Online Access: http://eprints.unisza.edu.my/7491/1/FH02-FSK-20-48832.pdf; http://eprints.unisza.edu.my/7491/
• Institution: Universiti Sultan Zainal Abidin

Plasmodium knowlesi is the fifth human malaria parasite widespread in the forested area of Southeast Asia. In Malaysia, there were increasing cases of this zoonotic knowlesi malaria from 1,600 to over 4,000 incidences from 2016 to 2018, with 12 deaths occurred in 2018. Plasmodium species are oblig...