Evaluation of preoperative duloxetine use for postoperative analgesia following laparoscopic cholecystectomy: a randomized controlled trial

• Main Authors: Mansour, Noha O., Boraii, Sherif, Elnaem, Mohamed Hassan Abdelaziz, Elrggal, Mahmoud E., Omar, Tamer, Abdelraouf, Amr, Abdelaziz, Doaa H.
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2022
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/100361/7/100361_Evaluation%20of%20preoperative%20duloxetine%20use%20for%20postoperative%20analgesia.pdf; http://irep.iium.edu.my/100361/; https://www.frontiersin.org/articles/10.3389/fphar.2022.944392/pdf; https://doi.org/10.3389/fphar.2022.944392
• Institution: Universiti Islam Antarabangsa Malaysia

Background: The pain pattern after laparoscopic cholecystectomy (LC) is complex and distinct from postoperative pain after other laparoscopic procedures, suggesting that procedure-specific optimal analgesic management plans should be proposed. Duloxetine, a non-opioid neuromodulator, has been widely...