In vitro, in silico and network pharmacology mechanistic approach to investigate the α-glucosidase inhibitors identified by Q-ToF-LCMS from phaleria macrocarpa fruit subcritical CO2 extract

• Main Authors: Rashid Mia, Md. Abdur, Ahmed, Qamar Uddin, Ferdosh, Sahena, Helal Uddin, A.B.M., Awal, Md. Shihabul, Sarian, Murni Nazira, Sarker, Md. Zaidul Islam, Zakaria, Zainul Amiruddin
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: QD Chemistry; RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/102370/7/102370_In%20vitro%2C%20in%20silico%20and%20network%20pharmacology%20mechanistic%20approach.pdf; http://irep.iium.edu.my/102370/; https://www.mdpi.com/journal/metabolites
• Institution: Universiti Islam Antarabangsa Malaysia

The fruit of Phaleria macrocarpa have been traditionally used as an antidiabetic remedy in Malaysia and neighbouring countries. Despite its potential for diabetes treatment, no scientific study has ever been conducted to predict the inhibitor interaction of the protein α-glucosidase identified in an e...