The role of solvent hydroxyl functional groups on the interaction energy and growth of form I paracetamol crystal facets

• Main Authors: Shahrir, Nurshahzanani, Anuar, Nornizar, Abdul Muttalib, Nur Aisyah, Yusop, Siti Nurul’ain, Abu Bakar, Mohd Rushdi, Adam, Fatmawati, Ibrahim, Siti Fatimah
• Format: Article
• Language: English; English
• Published: American Chemical Society (ACS Publication) 2022
• Subjects: QD Chemistry; RS192 Materia Medica-Pharmaceutical Technology; TP155 Chemical engineering
• Online Access: http://irep.iium.edu.my/102420/1/102420_The%20role%20of%20solvent%20hydroxyl%20functional%20groups.pdf; http://irep.iium.edu.my/102420/2/102420_The%20role%20of%20solvent%20hydroxyl%20functional%20groups_SCOPUS.pdf; http://irep.iium.edu.my/102420/; https://pubs.acs.org/doi/10.1021/acs.oprd.2c00151; https://doi.org/10.1021/acs.oprd.2c00151
• Institution: Universiti Islam Antarabangsa Malaysia

The morphology of a crystal grown in a solvent can change depending on the solvent used during the crystallization process. Modification of the morphology of a crystal can be engineered based on information conferred by the functional groups of the facets of interest and the functional groups of the...