Oral bullous pemphigoid induced by gabapentin: a case report

• Main Authors: Abd Rahman, Mohd Aizuddin, Shalihin, Mohd Shaiful Ehsan
• Format: Article
• Language: English
• Published: Universiti Teknologi MARA 2023
• Subjects: R Medicine (General); RA Public aspects of medicine; RB Pathology
• Online Access: http://irep.iium.edu.my/106610/7/106610_Oral%20bullous%20pemphigoid%20induced%20by%20gabapentin.pdf; http://irep.iium.edu.my/106610/; https://jchs-medicine.uitm.edu.my/images/manuscript/vol8issue2/03.case-report/10/10CR-September-2023-Oral-Bullous-Pemphigoid-Induced-by-Gabapentin.pdf; https://doi.org/10.24191/jchs.v8i2.13129
• Institution: Universiti Islam Antarabangsa Malaysia

Drug eruptions typically present with maculapapular rashes and blisters over the body and trunk. Gabapentin was rarely associated with bullous pemphigoid however, the link is still possible, involving localized oral lesions in which oral inspection is indeed essential. We reported a rare case of gabapentin induced oral bullous pemphigoid in an elderly patient who presented with localized lips and gums swelling. The association with gabapentin was almost missed due to the atypical presentation. We ceased the drug immediately. His condition improved by co-management with a dermatologist and application of high dose topical steroid. This case highlighted the importance of adequate history taking, thorough physical examination and immediate management of acute dermatological cases which can save the patient’s life.