Optimization of a two-dimensional electrophoresis protocol for plasma proteomic profiling of obese schizophrenia patients

• Main Authors: Mat Rasid, Siti Norain, Abd. Rahim, Nour El Huda, Mohamed Bakrim, Norbaiyah, A. Talib, Norlelawati, Abdull Jalil, Mohd Asyraf, Idorus, Mohd Yusri, Md Rosli, Ahmad Nabil
• Format: Article
• Language: English; English
• Published: Biome Scientia Sdn Bhd 2023
• Subjects: Q Science (General); QP Physiology; R Medicine (General); RC321 Neuroscience. Biological psychiatry. Neuropsychiatry
• Online Access: http://irep.iium.edu.my/109819/14/109819_Optimization%20of%20a%20two-dimensional%20electrophoresis%20protocol.pdf; http://irep.iium.edu.my/109819/15/109819_Optimization%20of%20a%20two-dimensional%20electrophoresis%20protocol_Supplemental.pdf; http://irep.iium.edu.my/109819/; https://biomescientia.com/index.php/lsmb/article/view/132
• Institution: Universiti Islam Antarabangsa Malaysia

The proteomic approach is particularly effective for studying the association between obesity and schizophrenia. It allows for a comprehensive analysis of the complete proteome, leading to substantial breakthroughs in biomarker discovery and drug development. Isoelectric focusing (IEF) and SDS-PAGE...