Repurposing natural products against Plasmodium Knowlesi lactate dehydrogenase via in Silico approach for antimalarial drug development

• Main Authors: Ahmad Fuad, Fazia Adyani, Mazahari, Muhammad Aiman Arif, Ogu Salim, Nurhainis
• Format: Article
• Language: English
• Published: Kulliyyah of Engineering, IIUM 2023
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://irep.iium.edu.my/110005/1/REPURPOSING%20NATURAL%20PRODUCTS%20AGAINST_koe.pdf; http://irep.iium.edu.my/110005/; https://journals.iium.edu.my/bnrej/index.php/bnrej/article/view/98
• Institution: Universiti Islam Antarabangsa Malaysia

Malaria cases have increased globally, which is due to the emergence of zoonotic malaria parasites that infect human, along with the existence of artemisinin-resistant parasites. Hence, there is an urgent need to find new therapeutics to counter these issues. As a vital enzyme...