Tumor shrinkage in a tamoxifen-treated non-functioning pituitary neuroendocrine tumor with positive estrogen receptor-beta (ERβ): a case report and review of the literature

• Main Authors: Haydar Ali Tajuddin, Amalina, Sukor, Norlela, Azizan, Elena Aisha, Kamaruddin, Nor Azmi, Omar, Ahmad Marzuki, Tan, Geok Chin, Mustangin, Muaatamarulain, Mohamed Mukari, Shahizon Azura, Alias, Azmi, Abd Latif, Kartikasalwah, Tay, Poh Sen, Idris, Nurdillah, Kasim, Fauziah, Wan Ismail, Wan Ruza Iswati
• Format: Article
• Language: English; English
• Published: Elsevier 2024
• Subjects: RC Internal medicine; RC254 Neoplasms. Tumors. Oncology (including Cancer); RC648 Specialties of Internal Medicine-Diseases of The Endocrine Glands. Clinical Endocrinology
• Online Access: http://irep.iium.edu.my/112977/2/112977_Tumor%20shrinkage%20in%20a%20tamoxifen-treated%20non-functioning.pdf; http://irep.iium.edu.my/112977/8/112977_Tumor%20shrinkage%20in%20a%20tamoxifen-treated%20non-functioning_Scopus.pdf; http://irep.iium.edu.my/112977/; https://www.sciencedirect.com/science/article/pii/S2214624524000133
• Institution: Universiti Islam Antarabangsa Malaysia

Administration of selective estrogen receptor modulators (SERMs) and anti-estrogens has been shown to reduce the size of pituitary tumors. However, previous studies were performed on animal pituitary tumors or tissue cultures. We administered oral tamoxifen to a postoperative patient with a nonfunct...