Four recurrent miscarriages – Is it a case of antiphospholipid syndrome?
Introduction: Antiphospholipid syndrome (APLS) is usually clinically suspected in antenatal women presented with recurrent miscarriages. Screening is usually conducted, especially for those with persistent, unexplained recurrent miscarriages in the first trimester. However, most patients might not...
Saved in:
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
2024
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/113054/2/113054_Four%20recurrent%20miscarriages%20%E2%80%93%20Is%20it%20a%20case%20of%20Antiphospholipid%20Syndrome.pdf http://irep.iium.edu.my/113054/ https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/806 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Universiti Islam Antarabangsa Malaysia |
Language: | English |
id |
my.iium.irep.113054 |
---|---|
record_format |
dspace |
spelling |
my.iium.irep.1130542024-07-10T00:26:04Z http://irep.iium.edu.my/113054/ Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? Roop Kishore, Yashdev Atri Shalihin, Mohd Shaiful Ehsan R Medicine (General) RA Public aspects of medicine RC Internal medicine RG Gynecology and obstetrics Introduction: Antiphospholipid syndrome (APLS) is usually clinically suspected in antenatal women presented with recurrent miscarriages. Screening is usually conducted, especially for those with persistent, unexplained recurrent miscarriages in the first trimester. However, most patients might not seek medical attention earlier, causing a delay in screening. Nevertheless, it is a dilemma for patients with recurrent miscarriages, especially up to four miscarriages, to be presumed as APLS until proven otherwise. Case: We reported a 37-year-old Gravida 5 Para 0+4 at four weeks of amenorrhoea presented with one episode of per vaginal bleeding. APLS and other relevant causative screenings had been performed, and the results were normal. Surprisingly, her pregnancy is still viable and progressing well. Discussion: This case proved that recurrent miscarriages on more than three occasions are not always equivalent to antiphospholipid syndrome. The underlying cause can be idiopathic or other causes that have not been investigated yet, including the possibility of a congenital anomaly. Conclusion: Suspicion of APLS is warranted and should be verified with the gold standard screening tests. In any case, where the results were normal, further assessments such as uterine evaluation, infectious disease screening, and pathological examination should be considered. Pre-pregnancy screening should be a minimal requirement for all women of reproductive age for the evaluation and prevention of similar outcomes to those of other women. 2024-07-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/113054/2/113054_Four%20recurrent%20miscarriages%20%E2%80%93%20Is%20it%20a%20case%20of%20Antiphospholipid%20Syndrome.pdf Roop Kishore, Yashdev Atri and Shalihin, Mohd Shaiful Ehsan (2024) Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? International Journal of Allied Health Sciences, 8 (2). pp. 3005-3008. E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/806 |
institution |
Universiti Islam Antarabangsa Malaysia |
building |
IIUM Library |
collection |
Institutional Repository |
continent |
Asia |
country |
Malaysia |
content_provider |
International Islamic University Malaysia |
content_source |
IIUM Repository (IREP) |
url_provider |
http://irep.iium.edu.my/ |
language |
English |
topic |
R Medicine (General) RA Public aspects of medicine RC Internal medicine RG Gynecology and obstetrics |
spellingShingle |
R Medicine (General) RA Public aspects of medicine RC Internal medicine RG Gynecology and obstetrics Roop Kishore, Yashdev Atri Shalihin, Mohd Shaiful Ehsan Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
description |
Introduction: Antiphospholipid syndrome (APLS) is usually clinically suspected in antenatal women
presented with recurrent miscarriages. Screening is usually conducted, especially for those with persistent,
unexplained recurrent miscarriages in the first trimester. However, most patients might not seek medical
attention earlier, causing a delay in screening. Nevertheless, it is a dilemma for patients with recurrent
miscarriages, especially up to four miscarriages, to be presumed as APLS until proven otherwise. Case: We
reported a 37-year-old Gravida 5 Para 0+4 at four weeks of amenorrhoea presented with one episode of per
vaginal bleeding. APLS and other relevant causative screenings had been performed, and the results were
normal. Surprisingly, her pregnancy is still viable and progressing well. Discussion: This case proved that
recurrent miscarriages on more than three occasions are not always equivalent to antiphospholipid
syndrome. The underlying cause can be idiopathic or other causes that have not been investigated yet,
including the possibility of a congenital anomaly. Conclusion: Suspicion of APLS is warranted and should
be verified with the gold standard screening tests. In any case, where the results were normal, further
assessments such as uterine evaluation, infectious disease screening, and pathological examination should be
considered. Pre-pregnancy screening should be a minimal requirement for all women of reproductive age for
the evaluation and prevention of similar outcomes to those of other women. |
format |
Article |
author |
Roop Kishore, Yashdev Atri Shalihin, Mohd Shaiful Ehsan |
author_facet |
Roop Kishore, Yashdev Atri Shalihin, Mohd Shaiful Ehsan |
author_sort |
Roop Kishore, Yashdev Atri |
title |
Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
title_short |
Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
title_full |
Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
title_fullStr |
Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
title_full_unstemmed |
Four recurrent miscarriages – Is it a case of antiphospholipid syndrome? |
title_sort |
four recurrent miscarriages – is it a case of antiphospholipid syndrome? |
publishDate |
2024 |
url |
http://irep.iium.edu.my/113054/2/113054_Four%20recurrent%20miscarriages%20%E2%80%93%20Is%20it%20a%20case%20of%20Antiphospholipid%20Syndrome.pdf http://irep.iium.edu.my/113054/ https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/806 |
_version_ |
1805880556711313408 |