Simple process capability analysis and quality validation of monoclonal antibody production in bench-top bioreactor

• Main Authors: Mel, Maizirwan, Arifin, Mohd Azmir, Kamaruddin, Mohd Hider, Abdul Karim, Mohamed Ismail, Yusof, Faridah
• Format: Article
• Language: English
• Published: Academic Journals 2011
• Subjects: TP155 Chemical engineering; TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/13646/1/Mel_et_al.pdf; http://irep.iium.edu.my/13646/; http://www.academicjournals.org/AJB/PDF/pdf2011/16DecConf/Mel%20et%20al.pdf
• Institution: Universiti Islam Antarabangsa Malaysia

The production of monoclonal antibody (MAbs) for anti-cancer by fermentation of hybridoma cell in bench-top bioreactor was investigated. The main aim of this study was to increase the percentage of cell viability and to achieve high yield of IgM. Many ways can be applied to improve the process and...