Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines

Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines

Fucoxanthin has been successfully isolated from species of Malaysian brown seaweed, namely P. australis. The purity of the fucoxanthin is >98% as indicated by High Performance Liquid Chromatography analysis. This seaweed also contained a considerable amount of unsaturated fatty acids. There are t...

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Main Authors: Noviendri, Dedi, Jaswir, Irwandi, Mohd. Salleh, Hamzah, Taher, Muhammad, Miyashita, Kazuo
Format: Conference or Workshop Item
Language:English
Published: 2011
Subjects:
TP Chemical technology
Online Access:http://irep.iium.edu.my/16360/1/Isolation_of_Fucoxanthin_and_fatty_acids_analysis.pdf
http://irep.iium.edu.my/16360/
http://www.iium.edu.my/icbioe/2011/
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English
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spelling my.iium.irep.163602021-06-03T04:16:46Z http://irep.iium.edu.my/16360/ Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines Noviendri, Dedi Jaswir, Irwandi Mohd. Salleh, Hamzah Taher, Muhammad Miyashita, Kazuo TP Chemical technology Fucoxanthin has been successfully isolated from species of Malaysian brown seaweed, namely P. australis. The purity of the fucoxanthin is >98% as indicated by High Performance Liquid Chromatography analysis. This seaweed also contained a considerable amount of unsaturated fatty acids. There are thirteen fatty acids were detected with Gas Chromatography. However, in terms of fatty acid methyl ester (FAMEs) of eicosapentanoic acid (C20:5n-3), arachidonic acid (C20:4n-6), linoleic acid (C18:2n-6) and alpha-linolenic acid (C18:3n-3) contents from P.australis was found (2.06, 9.50, 6.37, and 2.83 %, respectively). For saturated fatty acids, palmitic acid (C16:0) was found to be the major fatty acid about 23.97%. Furthermore, data obtained from the MTT assay indicated that fucoxanthin reduced the viability of H1299 cell lines, showing an IC50 value was 2.45 mM. 2011 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/16360/1/Isolation_of_Fucoxanthin_and_fatty_acids_analysis.pdf Noviendri, Dedi and Jaswir, Irwandi and Mohd. Salleh, Hamzah and Taher, Muhammad and Miyashita, Kazuo (2011) Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines. In: Proceedings of the 2nd International Conference on Biotechnology Engineering ICBioE'11, 17-19 May 2011, Kuala Lumpur. http://www.iium.edu.my/icbioe/2011/
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Noviendri, Dedi
Jaswir, Irwandi
Mohd. Salleh, Hamzah
Taher, Muhammad
Miyashita, Kazuo
Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
description Fucoxanthin has been successfully isolated from species of Malaysian brown seaweed, namely P. australis. The purity of the fucoxanthin is >98% as indicated by High Performance Liquid Chromatography analysis. This seaweed also contained a considerable amount of unsaturated fatty acids. There are thirteen fatty acids were detected with Gas Chromatography. However, in terms of fatty acid methyl ester (FAMEs) of eicosapentanoic acid (C20:5n-3), arachidonic acid (C20:4n-6), linoleic acid (C18:2n-6) and alpha-linolenic acid (C18:3n-3) contents from P.australis was found (2.06, 9.50, 6.37, and 2.83 %, respectively). For saturated fatty acids, palmitic acid (C16:0) was found to be the major fatty acid about 23.97%. Furthermore, data obtained from the MTT assay indicated that fucoxanthin reduced the viability of H1299 cell lines, showing an IC50 value was 2.45 mM.
format Conference or Workshop Item
author Noviendri, Dedi
Jaswir, Irwandi
Mohd. Salleh, Hamzah
Taher, Muhammad
Miyashita, Kazuo
author_facet Noviendri, Dedi
Jaswir, Irwandi
Mohd. Salleh, Hamzah
Taher, Muhammad
Miyashita, Kazuo
author_sort Noviendri, Dedi
title Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
title_short Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
title_full Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
title_fullStr Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
title_full_unstemmed Isolation of fuxoxanthin and fatty analysis from Padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (H1299) cell lines
title_sort isolation of fuxoxanthin and fatty analysis from padina australis and cytotoxicity effect of fucoxanthin of human lung cancer (h1299) cell lines
publishDate 2011
url http://irep.iium.edu.my/16360/1/Isolation_of_Fucoxanthin_and_fatty_acids_analysis.pdf
http://irep.iium.edu.my/16360/
http://www.iium.edu.my/icbioe/2011/
_version_ 1702169418610507776

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