Growth suppression of non-small lung carcinoma cell H1299 transfected with p53 and p73B

• Main Authors: Hayati, Rahma Fitri, Deny Susanti, Darnis, Arief Ichwan, Solachuddin Jauhari
• Format: Conference or Workshop Item
• Language: English
• Published: 2010
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/18158/1/Growth_suppression.pdf; http://irep.iium.edu.my/18158/; http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
• Institution: Universiti Islam Antarabangsa Malaysia

p53 gene has been hailed to have important roles in maintaining genomic integrity. The critical roles of this tumor suppressor in cell cycle, DNA repair, and opoptosis profoundly contribute to development of cancer. p53 mutations have been found in almost fifty percent of all cancer types, including...