Friedelin and lanosterol from Garcinia prainiana stimulated glucose uptake and adipocytes differentiation in 3T3-L1 adipocytes

• Main Authors: Darnis, Deny Susanti, Mohamed Amiroudine, Mohamed Zaffar Ali, Rezali, Mohd Fazlin, Bakhtiar, M. Taher
• Format: Article
• Language: English
• Published: Taylor & Francis 2012
• Subjects: Q Science (General)
• Online Access: http://irep.iium.edu.my/25776/1/Natural_product_Research.pdf; http://irep.iium.edu.my/25776/; http://www.tandfonline.com/doi/abs/10.1080/14786419.2012.725399?journalCode=gnpl20#preview
• Institution: Universiti Islam Antarabangsa Malaysia

Friedelin and lanosterol have been isolated from twigs of Garcinia prainiana.Their structures were elucidated by spectroscopic methods. The compounds were examined for their effects on 3T3-L1 adipocytes. In the MTT assay, it was found that the compounds had no cytotoxic effects up to 25 mM. Adipocy...