Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomized controlled trial of continuous infusion versus intermittent bolus administration

• Main Authors: Jamal, Janattul-Ain, Mat Nor, Mohd Basri, Mohamad Nor, Fariz Safhan, Udy, Andrew A, Wallis, Steven C, Lipman, Jeffrey, Roberts, Jason A.
• Format: Article
• Language: English
• Published: Elsevier 2015
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://irep.iium.edu.my/40454/1/pharmacokinetics_of_meropenem_IJAA.pdf; http://irep.iium.edu.my/40454/; http://www.journals.elsevier.com/international-journal-of-antimicrobial-agents; http://dx.doi.org/10.1016/j.ijantimicag.2014.09.009
• Institution: Universiti Islam Antarabangsa Malaysia

The objective of this study was to describe the pharmacokinetics of meropenem, administered by continuous infusion (CI) or intermittent bolus (IB), in critically ill patients receiving continuous venovenous haemofiltration (CVVH) and to evaluate the frequency of pharmacokinetic/pharmacodynamic targ...