Quantum chemical quantitative structure activity studies of anticancer activity of Aldohexose chloroethylnitrosourea Analogs

• Main Authors: Noorbatcha, Ibrahim Ali, Syed Osman Idid, Syed Zahir Idid, Eissa, Maimonah
• Format: Conference or Workshop Item
• Language: English
• Published: 2010
• Subjects: TP248.13 Biotechnology
• Online Access: http://irep.iium.edu.my/4099/4/ICAST2010_QSAR_%282%29.pdf; http://irep.iium.edu.my/4099/; http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=24&Itemid=19
• Institution: Universiti Islam Antarabangsa Malaysia

Quantitative structure activity relationship involving 18 aldohexose chloroethylnitrosourea compounds having anticancer activity against Ip-Implanted Murine L1210 Lymphoid Leukemia, is investigated using semi-empirical quantum chemical AM1 methods. Quantum chemical methods are used to calculate...