Comparison of the neurotoxic and myotoxic effects of two Moroccan scorpion venoms and their neutralization by experimental polyclonal antivenom

• Main Authors: Oukkache, Naoual, Ahmad Rusmili, Muhamad Rusdi, Othman, Iekhsan, Ghalim, Noreddine, Chgoury, Fatima, Boussadda, Lofti, Elmdaghri, Naima, Sabatier, Jean-Marc
• Format: Article
• Language: English; English
• Published: Life Science Journal 2015
• Subjects: QH Natural history; RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/42591/1/Paper_Noual_2015.pdf; http://irep.iium.edu.my/42591/4/42591_Comparison%20of%20the%20neurotoxic%20and%20myotoxic%20effects%20of%20two%20Moroccan%20scorpion%20venoms%20and%20their%20neutralization%20by%20experimental%20polyclonal%20antivenom_SCOPUS.pdf; http://irep.iium.edu.my/42591/; http://www.sciencedirect.com/science/article/pii/S002432051500051X
• Institution: Universiti Islam Antarabangsa Malaysia

Aims: Scorpion venoms contain complex mixtures of molecules, including peptides. These peptides specifically bind to various targets, in particular ion channels. Toxins modulating Na+, K+, Ca2+ and Cl − currents were described from venoms. The Androctonus and Buthus geni of scorpions are widely dis...