A hydrogel-actuated microvalve for smart flow control

In this paper, we report on the fabrication and testing of a hydrogel-actuated smart microvalve for biomedical applications. The three-layered microvalve is composed of a stimuli-sensitive ìintelligentî hydrogel sandwiched between a porous silicon membrane and a bossed PDMS flexible diaphragm. The...

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Main Authors: Lei, Ming, Wan Salim, Wan Wardatul Amani, Siegel, Ronald A., Ziaie, Babak
格式: Conference or Workshop Item
語言:English
出版: IEEE 2004
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在線閱讀:http://irep.iium.edu.my/44329/7/44329%20A%20Hydrogel-Actuated%20Microvalve.pdf
http://irep.iium.edu.my/44329/
https://ieeexplore.ieee.org/document/1403600
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總結:In this paper, we report on the fabrication and testing of a hydrogel-actuated smart microvalve for biomedical applications. The three-layered microvalve is composed of a stimuli-sensitive ìintelligentî hydrogel sandwiched between a porous silicon membrane and a bossed PDMS flexible diaphragm. The entrapped hydrogel in response to changes in the external physiological stimuli (e.g., pH, glucose, etc.), which diffuses through the porous membrane, swelles and deswelles hence deflecting the flexible PDMS diaphragm and controlling the closure and opening of the microvalve inlet. A microvalve incorporating a 155µm thick hydrogel (poly(methacrylic acid-co-acrylamide), mAA-co-AAm) has a response time of 3.6 min to a sudden pH change (pH=3 to pH=7).