Anti-stress properties of buprenorphine: a better choice for stress-induced relapse to drug addiction

• Main Authors: Ahmad Bidin, Mohammad Ashraf, Rosman, Nurul Nazierah, Suhaimi, Maryam Saadah, Syd Mohmad Faudzi, Syed Mohd Syahmi, Ridzwan, Irna Elina
• Format: Conference or Workshop Item
• Language: English
• Published: 2015
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/44337/1/44337.pdf; http://irep.iium.edu.my/44337/
• Institution: Universiti Islam Antarabangsa Malaysia

Compared to methadone, buprenorphine has a unique pharmacological profile in which it is a partial agonist at the mu- and NOP, but antagonist at the kappa-opioid receptors. This gives advantage to buprenorphine to have lesser abusive tendency and has ability to reduce relapse to drug taking. Previou...