Preparation, characterization and release profiles of insulin-loaded double-walled poly(lactide-co-glycolide) microspheres

• Main Authors: Rahman, Md. Mokhlesur, Ansary, Rezaul Haque, Katas, Haliza, Ab. Hadi, Hazrina, Mohamed, Awang
• Format: Conference or Workshop Item
• Language: English
• Published: 2015
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/44964/1/44964_abstract.pdf; http://irep.iium.edu.my/44964/; http://www.ukm.my/crdds/index.php/
• Institution: Universiti Islam Antarabangsa Malaysia

The aim of this study was to fabricate insulin-loaded double-walled poly(lactide-co-glycolide) (PLGA) microspheres using two different terminated PLGA (hydroxyl and carboxyl) to reduce the initial burst release as well as to remove the lag phase from the release profiles of insulin loaded PLGA micro...