A hydrophobic barrier deep within the inner pore of the ​TWIK-1 K2P potassium channel

Recent X-ray crystal structures of the two-pore domain (K2P) family of potassium channels have revealed a unique structural architecture at the point where the cytoplasmic bundle-crossing gate is found in most other tetrameric K+ channels. However, despite the apparently open nature of the inner por...

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Bibliographic Details
Main Authors: Aryal, Prafulla, Abd Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark, Stephen, Tucker
Format: Article
Language:English
English
Published: Nature Publishing Group 2014
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Online Access:http://irep.iium.edu.my/47584/1/47584.pdf
http://irep.iium.edu.my/47584/4/47584_A%20hydrophobic%20barrier%20deep_SCOPUS.pdf
http://irep.iium.edu.my/47584/
http://www.nature.com/ncomms/2014/140708/ncomms5377/full/ncomms5377.html
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English
English