Preparation, characterization and in vitro release studies of insulin-loaded double-walled poly(lactide-co-glycolide) microspheres

• Main Authors: Ansary, Md. Rezaul Haque, Rahman, Md. Mokhlesur, Awang, Mohamed, Katas, Haliza, Ab. Hadi, Hazrina, Abd Almonem, Doolaanea
• Format: Article
• Language: English; English
• Published: Springer 2016
• Subjects: QD Chemistry
• Online Access: http://irep.iium.edu.my/47774/1/Mokhles-DDTR-D-15-00072_R1.pdf; http://irep.iium.edu.my/47774/4/47774_Preparation%2C%20characterization_wos_scopus.pdf; http://irep.iium.edu.my/47774/; http://link.springer.com/article/10.1007%2Fs13346-016-0278-y
• Institution: Universiti Islam Antarabangsa Malaysia

The purpose of this study was to fabricate insulin-loaded double-walled and singlepolymer poly(lactide-co-glycolide) (PLGA) microspheres using a fast degrading glucose core, hydroxyl-terminated poly(lactide-co-glycolide) (Glu-PLGA) and a moderate degrading carboxyl-terminated PLGA polymers. A modifi...