Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus

Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three...

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Main Authors: Mohamed Ibrahim, Norlinah, Ngow, Harris Abdullah, BB, Hamidon
Format: Article
Language:English
Published: Singapore Medical Association 2007
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Online Access:http://irep.iium.edu.my/5000/1/4801cr1.pdf
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spelling my.iium.irep.50002013-06-10T03:34:51Z http://irep.iium.edu.my/5000/ Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus Mohamed Ibrahim, Norlinah Ngow, Harris Abdullah BB, Hamidon R Medicine (General) RB Pathology Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three-day history of right-sided limb weakness and aphasia. Cerebral computed tomography showed features of an acute infarct involving the left anterior and middle cerebral arteries. He was initially treated for an acute ischaemic stroke. Further history revealed that he was investigated for a growth in the sphenoid sinus two months earlier. Culture of the biopsied material from the sphenoid sinus grew Aspergillus fumigatus. Magnetic resonance imaging showed an extension of the growth to the brain, causing the acute ischaemic stroke. He was subsequently diagnosed with angioinvasive cerebral aspergillosis and was commenced on intravenous amphotericin B. Unfortunately, he succumbed to his illness despite treatment. Singapore Medical Association 2007 Article REM application/pdf en http://irep.iium.edu.my/5000/1/4801cr1.pdf Mohamed Ibrahim, Norlinah and Ngow, Harris Abdullah and BB, Hamidon (2007) Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus. Singapore Medical Journal, 48 (1). e1-4. ISSN 0037-5675 http://www.sma.org.sg/smj/4801/4801cr1.pdf
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic R Medicine (General)
RB Pathology
spellingShingle R Medicine (General)
RB Pathology
Mohamed Ibrahim, Norlinah
Ngow, Harris Abdullah
BB, Hamidon
Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
description Cerebral angioinvasive aspergillosis is a rare manifestation of disseminated aspergillosis which may result in stroke in immunocompromised individuals. Reports of such disease in patients with diabetes mellitus are rare. We describe a 45-year-old man with diabetes mellitus who presented with a three-day history of right-sided limb weakness and aphasia. Cerebral computed tomography showed features of an acute infarct involving the left anterior and middle cerebral arteries. He was initially treated for an acute ischaemic stroke. Further history revealed that he was investigated for a growth in the sphenoid sinus two months earlier. Culture of the biopsied material from the sphenoid sinus grew Aspergillus fumigatus. Magnetic resonance imaging showed an extension of the growth to the brain, causing the acute ischaemic stroke. He was subsequently diagnosed with angioinvasive cerebral aspergillosis and was commenced on intravenous amphotericin B. Unfortunately, he succumbed to his illness despite treatment.
format Article
author Mohamed Ibrahim, Norlinah
Ngow, Harris Abdullah
BB, Hamidon
author_facet Mohamed Ibrahim, Norlinah
Ngow, Harris Abdullah
BB, Hamidon
author_sort Mohamed Ibrahim, Norlinah
title Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_short Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_full Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_fullStr Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_full_unstemmed Angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
title_sort angioinvasive cerebral aspergillosis presenting as acute ischaemic stroke in a patient with diabetes mellitus
publisher Singapore Medical Association
publishDate 2007
url http://irep.iium.edu.my/5000/1/4801cr1.pdf
http://irep.iium.edu.my/5000/
http://www.sma.org.sg/smj/4801/4801cr1.pdf
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