Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management.

• Main Authors: Zin, Che Suraya, Nissen, Lisa M., O'Callaghan, James P., Moore, Brendan J., Smith, Maree T.
• Format: Article
• Language: English
• Published: Wiley Periodocals, Inc. 2010
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/5054/1/Che_Suraya_Article_1.pdf; http://irep.iium.edu.my/5054/; http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291526-4637
• Institution: Universiti Islam Antarabangsa Malaysia

Objective. This preliminary study assessed possible relationships between plasma and/or cerebrospinal fluid (CSF) concentrations of the pleiotropic cytokine,interleukin (IL)-6, the antiinflammatory cytokine, IL-10, and levels of pain reported by patients receiving intrathecal (i.t.)opioids. Design....