Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin

Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin

What is known and Objectives:  Testing for cytochrome P450-2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) variant alleles is recommended by the FDA for dosing of warfarin. However, dose prediction models derived from data obtained in one population may not be applicable to a...

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Bibliographic Details
Main Authors: Teh, L. K., Langmia, I. M., M. H., Fazleen Haslinda, Ngow, Harris Abdullah, Roziah, M. J., Harun, R., Zakaria, Z. A., Salleh, M. Z.
Format: Article
Language:English
Published: Blackwell Publishing 2011
Subjects:
QP Physiology
RC Internal medicine
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/5105/2/Cyp2c9_and_VKROC.pdf
http://irep.iium.edu.my/5105/
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English

Internet

http://irep.iium.edu.my/5105/2/Cyp2c9_and_VKROC.pdf
http://irep.iium.edu.my/5105/

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