Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents

Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents

Carbonic anhydrases (CA I, II, IX and XII) are known to be highly expressed in various human malignancies. CA IX is overexpressed in colorectal cancer specifically in hereditary nonpolyposis colorectal cancer. Inhibition of CA activity by small molecular CA inhibitor like sulphonamides, sulphonami...

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Main Authors: Alafeefy, Ahmed Mahmoud, Ahmad, Rehan, Abdulla, Maha, Eldehna, Wagdy M., Al-Tamimi, Abdul-Malek S., Abdel-Aziz, Hatem A., Al-Obaid, Omar, Carta, Fabrizio, Al-Kahtani, Abdulla A., Supuran, Claudiu T.
Format: Article
Language:English
Published: 2016
Subjects:
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/51718/1/EJMC.pdf
http://irep.iium.edu.my/51718/
http://www.sciencedirect.com/science/article/pii/S0223523416300010
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English

Internet

http://irep.iium.edu.my/51718/1/EJMC.pdf
http://irep.iium.edu.my/51718/
http://www.sciencedirect.com/science/article/pii/S0223523416300010

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