Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation

• Main Authors: Kamato, Danielle, Burch, Micah L., Piva, Terence J., Rezaei, Hossein B., Rostam, Muhamad Ashraf, Xu, Suowen, Zheng, Wenhua, Little, Peter J., Osman, Narin
• Format: Article
• Language: English
• Published: Elsevier 2013
• Subjects: QP Physiology
• Online Access: http://irep.iium.edu.my/55278/8/6.%20Kamato-2013-Transforming%20growth%20factor-%CE%B2%20signa.pdf; http://irep.iium.edu.my/55278/; http://www.sciencedirect.com/science/article/pii/S089865681300168X
• Institution: Universiti Islam Antarabangsa Malaysia

Transforming growth factor-β (TGF-β) is a secreted homodimeric protein that plays an important role in regulating various cellular responses including cell proliferation and differentiation, extracellular matrix production, embryonic development and apoptosis. Disruption of the TGF-β signalling path...