Determination of RUNX2 single nucleotide polymorphism rs6930053 in class I, II and III malocclusions

• Main Authors: Mokhtar@Makhtar, Khairani Idah, Abu Bakar, Noraini, Kharuddin, Azrul Fazwan
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2017
• Subjects: RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
• Online Access: http://irep.iium.edu.my/58834/2/KIM-IIDC%202017%20POSTER-Determination%20of%20RUNX2%20SNP%20rs6930053%20in%20Class%20I%2CII%20and%20III%20malocclusions.pdf; http://irep.iium.edu.my/58834/9/58834_abstract.pdf; http://irep.iium.edu.my/58834/; http://iidc.com.my/
• Institution: Universiti Islam Antarabangsa Malaysia

Introduction: Runt-related transcription factor 2 (RUNX2) plays important roles in osteoblast differentiation, tooth development and chondrocyte maturation; hence its involvement in craniofacial development is paramount. Mutation in RUNX2 is implicated with cleidocranial dysplasia; a bone developmen...