Evaluation of solvents’ effect on solubility, intermolecular interaction energies and habit of ascorbic acid crystals

• Main Authors: Hassan, Syajaratul Jahriah, Adam, Fatmawati, Abu Bakar, Mohd Rushdi, Abdul Mudalip, Siti Kholijah
• Format: Article
• Language: English; English; English
• Published: Elsevier B.V. 2019
• Subjects: RS Pharmacy and materia medica; RS192 Materia Medica-Pharmaceutical Technology
• Online Access: http://irep.iium.edu.my/59774/1/59774_Evaluation%20of%20solvents%E2%80%99%20effect%20on%20solubility.pdf; http://irep.iium.edu.my/59774/2/59774_Evaluation%20of%20solvents%E2%80%99%20effect%20on%20solubility_SCOPUS.pdf; http://irep.iium.edu.my/59774/3/59774_Evaluation%20of%20solvents%E2%80%99%20effect%20on%20solubility_WOS.pdf; http://irep.iium.edu.my/59774/; https://www.sciencedirect.com/science/article/pii/S1319610318300826#!
• Institution: Universiti Islam Antarabangsa Malaysia

Solubility of active pharmaceutical ingredient (API) in solvents is very important for drug development and manufacturing. Solubility data may provide further information such as thermochemical properties and intermolecular interactions that may lead to a better understanding of the formation of API...