Comparative assessment of poly (D, L-lactide-co-glycolide) nanoparticles modified by either cetyltrimethylammonium bromide or chitosan for plasmid DNA adsorption

• Main Authors: Doolaanea, Abd Almonem, Mansor, Nur 'Izzati, Nor, Nurul Hafizah Mohd, Mohd Shafri, Mohd Affendi, Susi, Sukmasari, Mohamed, Farahidah
• Format: Article
• Language: English; English
• Published: Faculty of Pharmacy, University of Benin, Benin City, Nigeria 2017
• Subjects: RS192 Materia Medica-Pharmaceutical Technology; RS403 Materia Medica-Pharmaceutical Chemistry
• Online Access: http://irep.iium.edu.my/60006/2/Comparative%20assessment%20of%20poly%20%28D%2CL-lactide-co-glycolide%29.pdf; http://irep.iium.edu.my/60006/8/Comparative%20assessment%20of%20poly%20%28D%2C%20L-lactide-co-glycolide%29%20nanoparticles%20modified%20by%20either%20cetyltrimethylammonium%20bromide%20or%20chitosan%20for%20plasmid%20DNA%20adsorption.pdf; http://irep.iium.edu.my/60006/; https://www.ajol.info/index.php/tjpr/article/view/162860
• Institution: Universiti Islam Antarabangsa Malaysia

Purpose: To evaluate poly (D,L-lactide-co-glycolide) PLGA nanoparticles modified by cetyltrimethyl ammonium bromide (CTAB) or chitosan for plasmid DNA adsorption. Methods: PLGA nanoparticles were prepared by solvent diffusion method and modified by including CTAB in the aqueous (F1) or oil phase...