Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts wer...
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Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English English |
Published: |
Taylor & Francis
2018
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Subjects: | |
Online Access: | http://irep.iium.edu.my/61762/1/SST-Tunna-Zaidul-2017.pdf http://irep.iium.edu.my/61762/7/61762-Enrichment%2C%20in%20vitro%2C%20and%20quantification%20study-SCOPUS.pdf http://irep.iium.edu.my/61762/ http://www.tandfonline.com/doi/abs/10.1080/01496395.2017.1384015 |
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Institution: | Universiti Islam Antarabangsa Malaysia |
Language: | English English |
Summary: | Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet
(CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol,
quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied.
Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment
levels. All three antidiabetic compounds were effectively enriched under optimized conditions of
temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet
method. Extraction conditions were seen to affect the enrichment of desired compounds. |
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