In silico study of carvone derivatives as potential neuraminidase inhibitors

• Main Authors: Jusoh, Noorakmar, Zainal, Hasanuddin, Abdul Hamid, Azzmer Azzar, Muhamad Bunnori, Noraslinda, Abd Halim, Khairul Bariyyah, Abd Hamid, Shafida
• Format: Article
• Language: English; English; English
• Published: Springer Berlin Heidelberg 2018
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://irep.iium.edu.my/63210/7/63210%20In%20silico%20study%20of%20carvone%20derivatives%20as%20potential%20neuraminidase%20inhibitors%20SCOPUS.pdf; http://irep.iium.edu.my/63210/13/63210_In%20silico%20study%20of%20carvone%20derivatives%20as%20potential%20neuraminidase%20inhibitors_article.pdf; http://irep.iium.edu.my/63210/19/63210_In%20silico%20study%20of%20carvone%20derivatives%20as%20potential%20neuraminidase%20inhibitors_WoS.pdf; http://irep.iium.edu.my/63210/; https://link.springer.com/article/10.1007/s00894-018-3619-6
• Institution: Universiti Islam Antarabangsa Malaysia

Recent outbreaks of highly pathogenic influenza strains have highlighted the need to develop new anti-influenza drugs. Here, we report an in silico study of carvone derivatives to analyze their binding modes with neuraminidase (NA) active sites. Two proposed carvone analogues, CV(A) and CV(B), with...