Novel sulfonamide derivatives carrying a biologically active 3,4-dimethoxyphenyl moiety as VEGFR-2 inhibitors

• Main Authors: Ghorab, Mostafa Mohammed, Alsaid, Mansour Sulaiman, Nissan, Yassin Mohammed, Ashour, Abdelkader Elbadawy Abbas, Al-Mishari, Abdullah Abdulalrahman, Kumar, Ashok, Ahmed, Sheikh Fayaz
• Format: Article
• Language: English; English
• Published: The Pharmaceutical Society of Japan 2016
• Subjects: RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/64278/13/64278%20Novel%20sulfonamide%20derivatives%20carrying%20a%20biologically%20active.pdf; http://irep.iium.edu.my/64278/14/64278%20Novel%20sulfonamide%20derivatives%20carrying%20a%20biologically%20active%20SCOPUS.pdf; http://irep.iium.edu.my/64278/; https://www.jstage.jst.go.jp/article/cpb/64/12/64_c16-00614/_pdf/-char/en
• Institution: Universiti Islam Antarabangsa Malaysia

Novel sulfonamides 3-19 with a biologically active 3,4-dimethoxyphenyl moiety were designed and synthesized. The structures of the synthesized compounds were established using elemental analyses, IR, 1H-NMR, 13C-NMR spectral data and mass spectroscopy. All the synthesized compounds were evaluated fo...