Identification of hyaluric acid synthesis 2 (has2) and gremlin 1 (grem1) gene expressions in human cumulus cells as a biomarker for oocyte quality.

• Main Authors: Abdul Wahab, Azantee Yazmie, Md Isa, Muhammad Lokman, Mohd Yassim, Haiyuni, Salleh, Yukmil Amru, Mat Yusof, Afzan, Abdul Razak, Redzuan Nul Hakim, Abdul Razak, Nik Fakhuruddin, Muhammad, Hussin, Mazlan, Muhammad Alif
• Format: Article
• Language: English; English
• Published: Malaysian Society for Biochemistry and Molecular Biology (MSBMB) 2019
• Subjects: R Medicine (General); RG Gynecology and obstetrics; RT Nursing
• Online Access: http://irep.iium.edu.my/76226/1/76226_Identification%20of%20Hyaluric%20Acid%20synthesis%202.pdf; http://irep.iium.edu.my/76226/7/76226_Identification%20of%20hyaluric%20acid%20synthesis%202%20%28HAS2%29%20and%20gremlin%201%20%28GREM1%29%20gene%20expressions%20in%20human%20cumulus%20cells%20as%20a%20biomarker%20for%20oocyte%20quality_Scopus.pdf; http://irep.iium.edu.my/76226/; https://drive.google.com/file/d/1Pgy1W5AC6pEMal9Aw9AaHCTXvNN0zF_9/view
• Institution: Universiti Islam Antarabangsa Malaysia

Nowadays, the criteria for oocyte selection is based on morphological criteria however, it needs further improvement to select the best embryo quality. The gene expression in the cumulus cell plays important role in signaling for follicular development as well as for oocyte quality. The aim of this...