The effect of maternal serum lipid on maternal blood pressure and fetal birth weight. A prospective Cohort Study at maternal child health centre

• Main Authors: Nusee, Zalina, Ho, Kah Seong, Abdullah, Suhaiza, Ismail, Hamizah
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2014
• Subjects: RG Gynecology and obstetrics
• Online Access: http://irep.iium.edu.my/79951/13/COGI%202014.pdf; http://irep.iium.edu.my/79951/14/poster%20COGI-2.pdf; http://irep.iium.edu.my/79951/
• Institution: Universiti Islam Antarabangsa Malaysia

Objective: To assess the social-demographic characteristic and the maternal risk factors for pre eclampsia (PE) especially maternal fasting serum lipids (FSL) between trimesters. It was also to find out the association between FSL with fetal birth weight at a primary maternal child health center (KKIA). Materials and methods: A prospective cohort study was designed for recruiting pregnant women who were in their 1st trimester at KKIA at Jalan Gambut Kuantan Pahang. The study involved taking fasting serum lipids (FSL), blood pressure (BP) measuring and urine albumin in every trimester. The data was analyzed using (SPSS) version 17.0 and p value of < 0.05 was considered as statistically significant. Results: Triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and total cholesterol (TC) were increased as the gestational age increased. The mean of TC surged from 5 mmol/L in 1st trimester to 7.4 mmol/L in 3rd trimester (p<0.05). A similar trend was also observed with TG, LDL and HDL. There were no significant changes in blood pressure and urine albumin throughout the pregnancy. Serum lipid did not statistically influence the birth weight (P>0.05). Meanwhile serum triglyceride level was double (4.5mmol/L) in one patient who developed eclampsia at 25 weeks gestation. Conclusion: Serum lipid increase in parallel to increase in gestational age, however it does not influenced the maternal blood pressure and birth weight. .�