Development of CRISPR-cas9 ribonucleoprotein complex platform for disruption of candidalysin in Candida albicans

The ECE1 gene encodes the ECE1 protein, which is processed into the toxic peptide, candidalysin in Candida albicans. Candidalysin is responsible for host epithelial cell damage and activation of the host cell inflammasome pathway during C. albicans colonization and proliferation, and is the most rec...

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Main Authors: Ahmad, Hasna, Ramzi, Ahmad Bazli, Arzmi, Mohd Hafiz
Format: Conference or Workshop Item
Language:English
English
Published: 2020
Subjects:
Online Access:http://irep.iium.edu.my/80885/1/arcsbproceedings_frontpage_abstract.pdf
http://irep.iium.edu.my/80885/2/ARCSB%20final%20slides_HASNA%20AHMAD.pdf
http://irep.iium.edu.my/80885/
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English
English