Effect of alpha-lipoic acid supplementation on blood pressure, renal oxidant-antioxidant status and renal damage in spontaneously hypertensive rats

• Main Authors: Govindasamy, Chandran, Kuttulebbai Naina Mohamed Salam, Sirajudeen
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/87618/1/AsianPacJTropBiomed_2019_9_10_415_269523%281%29.pdf; http://irep.iium.edu.my/87618/; https://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=10;spage=415;epage=423;aulast=Govindasamy;type=0
• Institution: Universiti Islam Antarabangsa Malaysia

Objective: To investigate the effect of alpha-lipoic acid (ALA) supplementation on systolic blood pressure (SBP), renal oxidant-antioxidant status and renal damage in spontaneously hypertensive rats (SHR) and SHR administered with Nω -nitro-L-arginine methyl ester (L-NAME). Methods: Male rats were...