A case series exploring the efficacy, secondary failure, paradoxical event & relapse with ustekinumab therapy in chronic plaque psoriasis

• Main Authors: Ismail, Rasimah, Jamil, Adawiyah, Md Nor, Norazirah
• Format: Article
• Language: English; English
• Published: Faculty of Medicine, Universiti Kebangsaan Malaysia 2020
• Subjects: RC Internal medicine; RL Dermatology
• Online Access: http://irep.iium.edu.my/87919/1/ustekinumab%20psoriasis%20Rasimah%20Ismail%20Medicine%20%26%20health%20.pdf; http://irep.iium.edu.my/87919/7/89719_A%20Case%20Series%20Exploring%20the%20Efficacy%2C%20Secondary%20Failure%2C%20Paradoxical%20Event_WOS.pdf; http://irep.iium.edu.my/87919/; http://www.medicineandhealthukm.com/sites/medicineandhealthukm.com/files/article/2020/15_ms0426_pdf_43746.pdf
• Institution: Universiti Islam Antarabangsa Malaysia

Ustekinumab is an anti-IL12/23 biologic agent used for treatment of psoriasis with excellent efficacy. However, there are therapeutic obstacles such as secondary failure and paradoxical event. Disease relapse upon discontinuation of therapy is common. A case series was performed on patients with ch...