Unilateral adrenal hyperplasia: a rare cause of primary aldosteronism

• Main Authors: Mahno, Noor Ezmas, Muhammad, Rohaizak, Abdul Shukur, Nordashima, Yaacob, Yazmin
• Format: Article
• Language: English; English
• Published: IIUM Press 2021
• Subjects: RD Surgery
• Online Access: http://irep.iium.edu.my/91079/3/91079_Unilateral%20adrenal%20hyperplasia%20a%20rare%20cause%20of%20primary%20aldosteronism_SCOPUS.pdf; http://irep.iium.edu.my/91079/4/91079_Unilateral%20adrenal%20hyperplasia%20a%20rare%20cause%20of%20primary%20aldosteronism.pdf; http://irep.iium.edu.my/91079/; https://journals.iium.edu.my/kom/index.php/imjm/article/download/1449/1145/7618; https://doi.org/10.31436/imjm.v20i2.1449
• Institution: Universiti Islam Antarabangsa Malaysia

A 73-year-old gentleman with a background history of long-standing hypertension and hyperlipidaemia presented with one-year history of persistent asymptomatic hypokalaemia associated with metabolic alkalosis. Within a few months, the hypertension worsened, needing increasing dose of anti-hypertensive agents. Biochemical test showed an elevated aldosterone-renin ratio but the computerized tomography (CT) scan of adrenal did not show any adrenal mass. Arterial stimulation venous sampling (ASVS) lateralized the lesion to the left side. A left retroperitoneal adrenalectomy was performed with immediate reversal of hypokalaemia and improvement of blood pressure control to only single anti-hypertensive agent.