The effect of prolonged fixation time on haematoxylin & eosin staining quality of rats colon and placenta tissue

• Main Authors: Mohd Radzuan, Hazulin, Saharudin, Shahida, Wan Omar, Wan Fatein Nabeila, Abd. Rahim, Nour El Huda, Halim, Mohd Dhiyaulhaq
• Format: Conference or Workshop Item
• Language: English; English
• Published: 2021
• Subjects: Q Science (General); QD Chemistry; QM Human anatomy; R Medicine (General)
• Online Access: http://irep.iium.edu.my/94042/1/IRD2021.pdf; http://irep.iium.edu.my/94042/2/ird2021%20ppt.pdf; http://irep.iium.edu.my/94042/
• Institution: Universiti Islam Antarabangsa Malaysia

The use of formalin in histopathological sample preparation is intended to preserve protein and cellular organelles. It is argued that prolonged formalin fixation may lead to tissue shrinkage and hardening. Reports on immunohistochemical studies showed that this does not cause reduction in antigen d...