Use of level specific ce-chirp auditory brainstem response with high rates and objective algorithm in infants population

• Main Authors: Chahed, Norashikin, Dzulkarnain, Ahmad Aidil Arafat, Jamaluddin, Saiful Adli
• Format: Conference or Workshop Item
• Language: English; English; English
• Published: 2021
• Subjects: RF Otorhinolaryngology; RJ Pediatrics
• Online Access: http://irep.iium.edu.my/95050/19/95050_Use_of_Level_Specific_poster.pdf; http://irep.iium.edu.my/95050/20/95050_Use_of_Level_Specific_paper.pdf; http://irep.iium.edu.my/95050/1/MYCIS2021-010.pdf; http://irep.iium.edu.my/95050/; https://mycis2021.com/2021/11/16/use-of-level-specific-ce-chirp-auditory-brainstem-response-with-high-rates-and-objective-algorithm-in-infants-population/
• Institution: Universiti Islam Antarabangsa Malaysia

Introduction: Universal Newborn Hearing Screening (UNHS) aims for early diagnosis, intervention, and follow-up of hearing-impaired babies. One of the tools used for the UNHS is the Auditory Brainstem Response (ABR). The LS CE Chirp is the recent innovated stimulus to elicit ABR and it is able to provide most neural synchrony in combination with high stimulus repetition rates and signal to noise ratio (SNR) objective algorithm, namely F-test at multiple points (Fmp). These techniques are potentially to reduce test time from the improvement in SNR of the ABRs recordings. This study aims to compare the ABR test time, amplitude, and absolute latencies of waves (I, III, and V), and threshold estimations among the ABRs obtained from the combinations of LS CE Chirp and Click stimuli at multiple intensity levels and stimulus repetition rates using both visual detection and objective SNR detection. Method: A total of 94 infants (68 normal hearing, 26 hearing-impaired) age less than 7 months participated. All participant have normal middle ear function and those 26 participants with hearing impairement has degree of hearing loss ranging from mild to severe. The ABRs were acquired using two stimuli (LS CE-Chirp and click) at 70 and 30 dBnHL. The test then continued up to the auditory threshold of each of the respective participant. The test was conducted using three stimulus repetition rates ( 81.1, 66.1, and 33.3 cps), and the signal averaging was stopped based on ; (i) F test at multiple points equal to 3.1(ii) visual detection (iii) fixed signal average at 2500 sweeps. Results: The results will be compared among the combinations of stimuli, stimulus repetition rates and stopping criteria using two-Way Repeated measure ANOVA at 95% confidence level. It is hypothesized that the ABR to LS CE Chirp combined with a high stimulus repetition rate and the objective algorithm will have a shorter test-time, larger amplitudes, and lower ABR threshold than the ABR to click stimulus, low stimulus repetition rate and wave identification using visual detection. Conclusion: High stimulus repetition rate LS CE-Chirp ABR and SNR objective algorithm may has the potential to efficiently determine auditory thresholds in infants, thus can serve as a methods for early diagnosis and intervention, lead to more functional hearing-impaired populations in the community.