Utility of small molecule TLR4 antagonist (+)-naltrexone in suppression of preterm birth induced in mice by platelet activating factor

Introduction: Microbial and sterile triggers of inflammation can activate Toll-like receptors (TLR) to initiate synthesis of pro-inflammatory cytokines that in turn drive the parturition cascade leading to preterm delivery (PTD). Platelet activating factor (PAF) has been identified as a key endogeno...

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Bibliographic Details
Main Authors: Robertson, Sarah, Wahid, Hanan Hamimi
Format: Article
Language:English
Published: IIUM Press 2018
Subjects:
Online Access:http://irep.iium.edu.my/98188/7/98188_Utility%20of%20small%20molecule%20TLR4%20antagonist.pdf
http://irep.iium.edu.my/98188/
https://journals.iium.edu.my/kom/index.php/imjm/article/view/931/631
https://doi.org/10.31436/imjm.v17i1.931
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Institution: Universiti Islam Antarabangsa Malaysia
Language: English