Utility of small molecule TLR4 antagonist (+)-naltrexone in suppression of preterm birth induced in mice by platelet activating factor
Introduction: Microbial and sterile triggers of inflammation can activate Toll-like receptors (TLR) to initiate synthesis of pro-inflammatory cytokines that in turn drive the parturition cascade leading to preterm delivery (PTD). Platelet activating factor (PAF) has been identified as a key endogeno...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
IIUM Press
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/98188/7/98188_Utility%20of%20small%20molecule%20TLR4%20antagonist.pdf http://irep.iium.edu.my/98188/ https://journals.iium.edu.my/kom/index.php/imjm/article/view/931/631 https://doi.org/10.31436/imjm.v17i1.931 |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English |