Exogenous metabolite feeding on altering antibiotic susceptibility in Gram-negative bacteria through metabolic modulation: a review

• Main Authors: Chung, Wan Yean, Zhu, Yan, Mahamad Maifiah, Mohd Hafidz, Hawala Shivashekaregowda, Naveen Kumar, Wong, Eng Hwa, Abdul Rahim, Nusaibah
• Format: Article
• Language: English
• Published: Springer Nature 2022
• Subjects: QR Microbiology; RM Therapeutics. Pharmacology; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/98676/7/98676_Exogenous%20metabolite%20feeding%20on%20altering%20antibiotic%20susceptibility.pdf; http://irep.iium.edu.my/98676/; https://link.springer.com/article/10.1007/s11306-022-01903-w
• Institution: Universiti Islam Antarabangsa Malaysia

Background The rise of antimicrobial resistance at an alarming rate is outpacing the development of new antibiotics. The worrisome trends of multidrug-resistant Gram-negative bacteria have enormously diminished existing antibiotic activity. Antibiotic treatments may inhibit bacterial growth or lead...