Evaluation of human embryonic stem cells and their differentiatedfibroblastic progenies as cellular models for in vitro genotoxicity screening

This study evaluated human embryonic stem cells (hESC) and their differentiated fibroblastic progeniesas cellular models for genotoxicity screening. The DNA damage response of hESCs and their differentiated fibroblastic progenies were compared to a fibroblastic cell line (HEPM, CRL1486) and primary...

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Bibliographic Details
Main Authors: Vinoth, Kumar Jayaseelan, Manikandan, Jayapal, Sethu, Swaminathan, Balakrishan, Lakshmidevi, Heng, Alexis Boon Chin *, Lu, Kai, Hande, Manoor Prakash, Cao, Tong
Format: Article
Published: Elsevier 2014
Subjects:
Online Access:http://eprints.sunway.edu.my/265/
http://www.sciencedirect.com/science/article/pii/S0168165614002405
http://dx.doi.org/10.1016/j.jbiotec.2014.05.009
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Institution: Sunway University