COVID-19 therapeutic potential of natural products
Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still one of the leading causes of death in 2022. The availability of COVID-19 vaccines, FDA-approved antivirals, and mon...
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my.sunway.eprints.27192024-07-03T06:57:04Z http://eprints.sunway.edu.my/2719/ COVID-19 therapeutic potential of natural products Low, Zhao Xuan Rafidah, Lani Tiong, Vunjia Poh, Chit Laa * Sazaly, Abu Bakar Pouya, Hassandarvish QD Chemistry QK Botany RA Public aspects of medicine Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still one of the leading causes of death in 2022. The availability of COVID-19 vaccines, FDA-approved antivirals, and monoclonal antibodies in low-income countries still poses an issue to be addressed. Natural products, particularly traditional Chinese medicines (TCMs) and medicinal plant extracts (or their active component), have challenged the dominance of drug repurposing and synthetic compound libraries in COVID-19 therapeutics. Their abundant resources and excellent antiviral performance make natural products a relatively cheap and readily available alternative for COVID-19 therapeutics. Here, we deliberately review the anti-SARS-CoV-2 mechanisms of the natural products, their potency (pharmacological profiles), and application strategies for COVID-19 intervention. In light of their advantages, this review is intended to acknowledge the potential of natural products as COVID-19 therapeutic candidates. MDPI 2023 Article PeerReviewed Low, Zhao Xuan and Rafidah, Lani and Tiong, Vunjia and Poh, Chit Laa * and Sazaly, Abu Bakar and Pouya, Hassandarvish (2023) COVID-19 therapeutic potential of natural products. International Journal of Molecular Sciences, 24 (11). ISSN 1422-0067 https://doi.org/10.3390/ijms24119589 10.3390/ijms24119589 |
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QD Chemistry QK Botany RA Public aspects of medicine Low, Zhao Xuan Rafidah, Lani Tiong, Vunjia Poh, Chit Laa * Sazaly, Abu Bakar Pouya, Hassandarvish COVID-19 therapeutic potential of natural products |
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Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still one of the leading causes of death in 2022. The availability of COVID-19 vaccines, FDA-approved antivirals, and monoclonal antibodies in low-income countries still poses an issue to be addressed. Natural products, particularly traditional Chinese medicines (TCMs) and medicinal plant extracts (or their active component), have challenged the dominance of drug repurposing and synthetic compound libraries in COVID-19 therapeutics. Their abundant resources and excellent antiviral performance make natural products a relatively cheap and readily available alternative for COVID-19 therapeutics. Here, we deliberately review the anti-SARS-CoV-2 mechanisms of the natural products, their potency (pharmacological profiles), and application strategies for COVID-19 intervention. In light of their advantages, this review is intended to acknowledge the potential of natural products as COVID-19 therapeutic candidates. |
format |
Article |
author |
Low, Zhao Xuan Rafidah, Lani Tiong, Vunjia Poh, Chit Laa * Sazaly, Abu Bakar Pouya, Hassandarvish |
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Low, Zhao Xuan Rafidah, Lani Tiong, Vunjia Poh, Chit Laa * Sazaly, Abu Bakar Pouya, Hassandarvish |
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Low, Zhao Xuan |
title |
COVID-19 therapeutic potential of natural products |
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COVID-19 therapeutic potential of natural products |
title_full |
COVID-19 therapeutic potential of natural products |
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COVID-19 therapeutic potential of natural products |
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COVID-19 therapeutic potential of natural products |
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covid-19 therapeutic potential of natural products |
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MDPI |
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2023 |
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http://eprints.sunway.edu.my/2719/ https://doi.org/10.3390/ijms24119589 |
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