Comparison of cancer stem cell enrichment between spheroids derived from single-cell and multicellular aggregate cultures

• Main Authors: Omar, Nafiis Hairuddin, Badrul, Hisham Yahaya, Mohamad Johari, Ibahim, Abhi, Veerakumarasivam *, Chan, Soon Choy, Musalmah, Mazlan, Nurhidaya, Ab. Rahim, Syarifah Masyitah, Habib Dzulkarnain, Siti Farizan, Mansor
• Format: Article
• Published: Biomedpress 2023
• Subjects: RC Internal medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/2885/; http://bmrat.org/index.php/BMRAT/article/view/823
• Institution: Sunway University

Introduction: Cancer stem cells (CSCs) represent a distinct group of cells within cancerous tissue that possess the ability to initiate tumorigenesis and exhibit potency, self-renewal, and drug resistance. The study of CSCs often encounters challenges in obtaining these cells of interest or generati...